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ONC-ORG

Cancer Drug Encyclopedia

Approved oncology medications — what they treat, how they work and key safety information.

Omacetaxine MepesuccinateOmacetaxine Mepesuccinate
Targeted Oncology AgentOral Tablet / Capsule

Approved for use in oncology care according to FDA-approved indications.

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OncasparPegaspargase
Targeted Oncology AgentOral Tablet / Capsule

Approved for use in oncology care according to FDA-approved indications.

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Ondansetron HydrochlorideOndansetron Hydrochloride
Antiemetic Supportive Agent (5-HT3 / NK1 Receptor Antagonist)Oral Tablet / Intravenous Solution

Prevention and management of chemotherapy-induced and radiation-induced nausea and vomiting (CINV).

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OnivydeIrinotecan Sucrosofate
Topoisomerase Inhibitor Chemotherapy AgentIntravenous Solution for Infusion

Breast Cancer, Small Cell Lung Cancer, Colorectal Cancer, Ovarian Cancer, and Acute Leukemias.

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OnuregAzacitidine
Cytotoxic Antimetabolite Chemotherapeutic AgentLyophilized Powder / Solution for Intravenous Infusion

Colorectal, Pancreatic, Breast, Non-Small Cell Lung Cancer, Myelodysplastic Syndromes (MDS), and Acute/Chronic Leukemias.

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Opdivonivolumab
Immune Checkpoint Inhibitor (PD-1 / PD-L1 / CTLA-4)Intravenous Solution / Subcutaneous Injection

Advanced melanoma, metastatic non-small cell lung cancer, malignant pleural mesothelioma, advanced renal cell carcinoma, classical Hodgkin lymphoma, squamous cell carcinoma of the head and neck, urothelial carcinoma, and MSI-H/dMMR metastatic colorectal cancer.

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Opdivo QvantigNivolumab and Hyaluronidase-nvhy
Immune Checkpoint Inhibitor (PD-1 / PD-L1 / CTLA-4)Intravenous Solution / Subcutaneous Injection

Melanoma, Non-Small Cell Lung Cancer, Renal Cell Carcinoma, Urothelial Cancer, Head and Neck Cancer, MSI-H/dMMR solid tumors, and Cervical Cancer.

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OpdualagNivolumab and Relatlimab-rmbw
Immune Checkpoint Inhibitor (PD-1 / PD-L1 / CTLA-4)Intravenous Solution / Subcutaneous Injection

Melanoma, Non-Small Cell Lung Cancer, Renal Cell Carcinoma, Urothelial Cancer, Head and Neck Cancer, MSI-H/dMMR solid tumors, and Cervical Cancer.

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OrgovyxRelugolix
GnRH / LHRH Agonist or AntagonistOral Daily Tablet

Advanced Prostate Cancer and Premenopausal Hormone-Receptor Positive Breast Cancer.

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OrserduElacestrant Dihydrochloride
Selective Estrogen Receptor Modulator / Degrader (SERM/SERD)Oral Tablet

HR-positive Breast Cancer in adjuvant, metastatic, and chemoprevention settings.

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Osimertinib MesylateOsimertinib Mesylate
EGFR Tyrosine Kinase InhibitorOral Film-Coated Tablet / Capsule

EGFR-mutated Non-Small Cell Lung Cancer (NSCLC).

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OxaliplatinOxaliplatin
Platinum Coordination Complex Chemotherapeutic AgentIntravenous Solution for Infusion

Testicular, Ovarian, Bladder, Lung, Colorectal, Gastric, and Head & Neck Cancers.

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