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ONC-ORG

Cancer Drug Encyclopedia

Approved oncology medications — what they treat, how they work and key safety information.

Leuprolide MesylateLeuprolide Mesylate
GnRH / LHRH Agonist or AntagonistSubcutaneous / Intramuscular Depot Injection

Advanced Prostate Cancer and Premenopausal Hormone-Receptor Positive Breast Cancer.

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Levulan KerastickAminolevulinic Acid Hydrochloride
Targeted Oncology AgentOral Tablet / Capsule

Approved for use in oncology care according to FDA-approved indications.

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LibtayoCemiplimab-rwlc
Immune Checkpoint Inhibitor (PD-1 / PD-L1 / CTLA-4)Intravenous Solution / Subcutaneous Injection

Melanoma, Non-Small Cell Lung Cancer, Renal Cell Carcinoma, Urothelial Cancer, Head and Neck Cancer, MSI-H/dMMR solid tumors, and Cervical Cancer.

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LifileucelLifileucel
Autologous CAR T-Cell ImmunotherapySingle-dose Intravenous Suspension for Infusion

Relapsed or refractory B-cell Acute Lymphoblastic Leukemia, Large B-cell Lymphoma, Mantle Cell Lymphoma, or Multiple Myeloma.

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Lisocabtagene MaraleucelLisocabtagene Maraleucel
Autologous CAR T-Cell ImmunotherapySingle-dose Intravenous Suspension for Infusion

Relapsed or refractory B-cell Acute Lymphoblastic Leukemia, Large B-cell Lymphoma, Mantle Cell Lymphoma, or Multiple Myeloma.

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LomustineLomustine
DNA Alkylating Chemotherapeutic AgentOral Capsule

Brain Tumors (Glioblastoma, Astrocytoma), Multiple Myeloma, Lymphomas, Leukemias, Sarcomas, and conditioning regimens.

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Loncastuximab Tesirine-lpylLoncastuximab Tesirine-lpyl
Targeted Antibody-Drug Conjugate (ADC)Lyophilized Powder for Intravenous Infusion

Advanced or metastatic solid tumors or hematologic malignancies expressing targeted surface antigens.

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LonsurfTrifluridine and Tipiracil Hydrochloride
Cytotoxic Antimetabolite Chemotherapeutic AgentLyophilized Powder / Solution for Intravenous Infusion

Colorectal, Pancreatic, Breast, Non-Small Cell Lung Cancer, Myelodysplastic Syndromes (MDS), and Acute/Chronic Leukemias.

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LoqtorziToripalimab-tpzi
Immune Checkpoint Inhibitor (PD-1 / PD-L1 / CTLA-4)Intravenous Solution / Subcutaneous Injection

Melanoma, Non-Small Cell Lung Cancer, Renal Cell Carcinoma, Urothelial Cancer, Head and Neck Cancer, MSI-H/dMMR solid tumors, and Cervical Cancer.

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LorbrenaLorlatinib
ALK / ROS1 Tyrosine Kinase InhibitorOral Film-Coated Tablet / Capsule

ALK-positive and ROS1-positive metastatic Non-Small Cell Lung Cancer.

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LorlatinibLorlatinib
ALK / ROS1 Tyrosine Kinase InhibitorOral Film-Coated Tablet / Capsule

ALK-positive and ROS1-positive metastatic Non-Small Cell Lung Cancer.

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LumakrasSotorasib
KRAS G12C Specific InhibitorOral Film-Coated Tablet / Capsule

KRAS G12C-mutated Non-Small Cell Lung Cancer and advanced Colorectal Cancer.

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